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KMID : 0895019990020010055
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Chungnam Journal of Nursing Academy
1999 Volume.2 No. 1 p.55 ~ p.66
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Effects of EPO medication on Subjective change, ADL, and QOL for CRF patients
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Cheong Ae-Ran
Kim Hyun-Li
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Abstract
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This study was performed to investigate the effects of Epo medication effect on subjective changes, ADL, and QOL in the process of treatment for chronic renal failure patients. The total of 62 CRF patients who are receiving hemodialysis with EPO medication participated in the study. The data collection period was from July, 2, 1998 to August 14, 1998. The survey data were analyzed utilizing SAS program. The results were as follows. 1. The most frequent underlying disease that required EPO medication for chronic renal failure (CRF) patients was Diabetes Mellitus (32.3%). The values of Hb and Hct were proportionally increased according to the dosage of EPO medication. 2. The mean of ADL score was 4.29 representing relatively high independence of the subjects, and the lowest scored item was “Doing the housework” (M = 3.72). 3. The Subjective physical changes while receiving Epo medication were assessed by 17 items. The CRF patients reported the item of “I have better appetite” as the most improved one (M = 3.93), while the item of “I have better sexual need” was reported with a relatively lower mean score 2.36. The reported QOL mean score for CRF patients with Epo medication in this study was lower than that of previous research results. 4. The mean scores of QOL (t = -2.97, D = 0.0043) and ADL (t = -3.57, p = 0.0007) for the CRF patients with Diabetes Mellitus were lower compare to the patients with other causal diseases. 5. There was positive correlation between the ADL and QOL scores (r = 0.34, p = 0.005). 6. The values of Hct(t = -3.59, p= 0.0002) as well as Hb(t = -4.31, p = 0.0001) were significantly increased in one month after Epo medication.
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